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Primary Sjögren's disease and its complications presenting with progressive paralysis.

Julian, Matthew and Chakravorty, Trishna and Dyer, Philip (2011) Primary Sjögren's disease and its complications presenting with progressive paralysis. BMJ Case Reports, 2011. p. 3347. ISSN 1757-790X.

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Official URL: http://casereports.bmj.com/cgi/pastseven?fdate=1/1...

Abstract

A 24-year-old female presented with generalised weakness, lethargy and aches in legs. She was subsequently found to be markedly hypokalaemic and have a metabolic acidosis. A diagnosis of distal renal tubular acidosis (RTA) was made. In addition to this failure to alkalinise her urine, she was unable to concentrate it and so a diagnosis of nephrogenic diabetes insipidus was reached. Further questioning revealed previous investigation of a connective tissue disorder thought to be primary Sjögren's syndrome. RTA is a recognised but rare complication of Sjögren's syndrome. Urinary alkalinisation using potassium bicarbonate was instituted; the patient responded well to treatment and is having outpatient follow-up.

Item Type: Article
Subjects: WD Diseases and disorders of systemic, metabolic or environmental origin
WK Endocrine system. Endocrinology
Divisions: Ambulatory Care > Diabetes
Related URLs:
Depositing User: Mrs Caroline Tranter
Date Deposited: 15 May 2013 08:21
Last Modified: 15 May 2013 08:21
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/78

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