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Lymphoproliferative disorder due to sulphasalazine.

Dubey, Shirish and Adebajo, A O (2009) Lymphoproliferative disorder due to sulphasalazine. BMJ Case Reports, 2009. ISSN 1757-790X.

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Official URL: http://casereports.bmj.com/content/2009/bcr.06.200...

Abstract

We present the case of a 57-year-old man who had been on sulphasalazine for 20 years for seropositive non-erosive rheumatoid arthritis and developed a lymphoproliferative disorder, which resolved completely on cessation of sulphasalazine. This is the first report of lymphoproliferative disorder secondary to sulphasalazine. Lymphoproliferative disorders are well recognised with methotrexate and cyclosporine, and recognition of this disorder is critical due to the fact that a number of patients' symptoms will resolve completely with discontinuation of the drug and will not need further treatment. This case report discusses the literature on lymphoproliferative disorders as well as differential diagnoses like drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.

Item Type: Article
Subjects: WH Haemic and lymphatic systems. Haematology
Divisions: Ambulatory Care > Rheumatology
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Depositing User: Users 6 not found.
Date Deposited: 13 May 2013 12:26
Last Modified: 13 May 2013 12:26
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/50

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