Davies, Robert S M and Abdelhamid, Mohamed and Vohra, Rajiv K and Bradbury, Andrew W and Adam, Donald J (2011) Perioperative myocardial injury and hemostasis in patients undergoing endovascular aneurysm repair for asymptomatic infrarenal abdominal aortic aneurysm. Vascular and endovascular surgery, 45 (8). pp. 712-6. ISSN 1938-9116.Full text not available from this repository.
(1) To report the incidence of myocardial injury in patients undergoing endovascular aortic aneurysm repair (EVAR) through the routine measurement of perioperative cardiac troponin-T (cTnT) and (2) to investigate and correlate changes in perioperative cTnT levels with any concomitant hemostatic derangement.
Prospective study of 30 patients undergoing elective EVAR for infrarenal abdominal aortic aneurysm. Cardiac TnT was assayed at 24 hours postoperatively. Plasma thrombin antithrombin III complex (TAT), plasminogen activator inhibitor 1 (PAI-1), tissue plasminogen activator (t-PA) activity, and soluble P-selectin (sP-selectin) were assayed preoperatively and at 24 hours postoperatively.
Five (17%) patients demonstrated elevated cTnT levels at 24 hours; 3 patients had no clinical evidence of myocardial injury. There was a positive correlation between cTnT and TAT levels at 24 hours post-EVAR (r = .38, P = .039, Kendall-tau B = 0.26).
Endovascular aortic aneurysm repair is associated with a significant risk of perioperative myocardial injury that is underdetected clinically and associated with a procoagulopathic state.
|Subjects:||WG Cardiovascular system. Cardiology|
|Divisions:||Planned IP Care > Vascular|
|Depositing User:||Mrs Caroline Tranter|
|Date Deposited:||18 Aug 2014 13:08|
|Last Modified:||18 Aug 2014 13:08|
Actions (login required)