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Shift work effects on serial PEF measurements for occupational asthma.

Moore, V C and Jaakkola, M S and Burge, C B S G and Pantin, C F A and Robertson, A S and Burge, P Sherwood (2012) Shift work effects on serial PEF measurements for occupational asthma. Occupational medicine (Oxford, England), 62 (7). pp. 525-32. ISSN 1471-8405. This article is accessible to all HEFT staff and students via NHS Evidence www.evidence.nhs.uk by using their HEFT Athens login IDs

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Official URL: http://occmed.oxfordjournals.org/content/62/7.toc

Abstract

BACKGROUND

Diurnal variation (DV) affects lung function but the changes are thought to be related to sleep patterns rather than time of day. When diagnosing occupational asthma (OA), serial peak expiratory flow (PEF) measurements are the recommended first line investigation, but could be confounded by shift work.

AIMS

The aim of the study was to investigate the effects of shift work on PEF measurements used for diagnosing OA.

METHODS

PEF records containing more than one shift pattern with ≥ 4 days per shift were identified. OA diagnosis was based on an Oasys-2 score ≥ 2.51 and non-OA on having an alternative clinical diagnosis and Oasys-2 score <2.51. The mean area between curves (ABC) score, mean PEF DV and cross-shift PEF changes were calculated for each shift.

RESULTS

Records from 123 workers with OA and 69 without OA satisfied inclusion criteria. In the OA group, PEF declined more on afternoon and night shifts than days (P < 0.001). The ABC score was lower in the OA group on night (P < 0.05) and afternoon shifts (P < 0.05) as compared with days, without significant differences in DV. Among those without OA, cross-shift PEF increased more on day shifts (mean + 25 l/min) than afternoon or night shifts (+1 l/min) (P < 0.001). The sensitivity for the ABC score and DV were good and similar across shifts, but specificity was reduced using DV (DV mean 39%; ABC 98%).

CONCLUSIONS

PEF responses between work and rest show small differences according to shift type. The ABC score has a high sensitivity and specificity for all shifts; differences in DV have lower specificity.

Item Type: Article
Additional Information: This article is accessible to all HEFT staff and students via NHS Evidence www.evidence.nhs.uk by using their HEFT Athens login IDs
Subjects: W Public health. Health statistics. Occupational health. Health education
WF Respiratory system. Respiratory medicine
Divisions: Planned IP Care > Respiratory Medicine
Planned IP Care > Thoracic Surgery
Related URLs:
Depositing User: Mrs Yolande Brookes
Date Deposited: 14 Aug 2014 12:13
Last Modified: 14 Aug 2014 12:13
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/437

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