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Key considerations around the risks and consequences of hypoglycaemia in people with type 2 diabetes.

Barnett, A H and Cradock, S and Fisher, M and Hall, G and Hughes, E and Middleton, A (2010) Key considerations around the risks and consequences of hypoglycaemia in people with type 2 diabetes. International journal of clinical practice, 64 (8). pp. 1121-9. ISSN 1742-1241. Full Text Available via Wiley link

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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1742-...

Abstract

Hypoglycaemia and its consequences represent a significant risk for many people who have type 2 diabetes, and hypoglycaemia is currently under-recognised and commonly avoidable. Current clinical guidelines recommend the targeting of tight glycaemic control and this strategy may also be associated with an increased risk of hypoglycaemia. Hypoglycaemia impacts on morbidity, mortality and quality of life of people with type 2 diabetes, and improved recognition of the symptoms of hypoglycaemia will allow effective treatment and reduce the risk of progression to more severe episodes. A common cause of hypoglycaemia in people with type 2 diabetes is glucose-lowering medication, in particular, those which raise insulin independently of ambient glucose concentration such as sulphonylureas and exogenous insulin. The recently published National Institute for Health and Clinical Excellence guideline recommends the use of Dipeptidyl peptidase-4 inhibitors or thiazolidinediones (glitazones) as alternative second-line therapy instead of a sulphonylurea in those patients who are at significant risk of hypoglycaemia and its consequences.

Item Type: Article
Additional Information: Full Text Available via Wiley link
Subjects: WK Endocrine system. Endocrinology
Divisions: Ambulatory Care > Diabetes
Related URLs:
Depositing User: Sophie Rollason
Date Deposited: 25 Jun 2014 11:07
Last Modified: 25 Jun 2014 11:07
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/322

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