Earlier and enhanced rehabilitation of mechanically ventilated patients in critical care: A feasibility randomised controlled trial.

McWilliams, David and Jones, Charlotte and Atkins, Gemma and Hodson, James and Whitehouse, Tony and Veenith, Tonny and Reeves, Emma and Cooper, Lauren and Snelson, Catherine (2018) Earlier and enhanced rehabilitation of mechanically ventilated patients in critical care: A feasibility randomised controlled trial. Journal of critical care, 44. pp. 407-412. ISSN 1557-8615. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Abstract

BACKGROUND

Systematic reviews of early rehabilitation within intensive care units have highlighted the need for robust multi-centre randomised controlled trials with longer term follow up. This trial aims to explore the feasibility of earlier and enhanced rehabilitation for patients mechanically ventilated for ≥5days and to assess the impact on possible long term outcome measures for use in a definitive trial.

METHODS

Patients admitted to a large UK based intensive care unit and invasively ventilated for ≥5days were randomised to the rehabilitation intervention or standard care on a 1:1 basis, stratified by age and SOFA score. The rehabilitation intervention involved a structured programme, with progression along a functionally based mobility protocol according to set safety criteria.

RESULTS

103 out of 128 eligible patients were recruited into the trial, achieving an initial recruitment rate of 80%. Patients in the intervention arm mobilized significantly earlier (8days vs 10 days, p=0.035), at a more acute phase of illness (SOFA 6 vs 4, p<0.05) and reached a higher level of mobility at the point of critical care discharge (MMS 7 vs 5, p<0.01).

CONCLUSION

We have demonstrated the feasibility of introducing a structured programme of rehabilitation for patients admitted to critical care.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WX Health services
Divisions: Clinical Support > Critical Care
Related URLs:
Depositing User: Mrs Semanti Chakraborty
Date Deposited: 01 Apr 2019 11:18
Last Modified: 01 Apr 2019 11:18
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1987

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