Depression and the dermatologist: a critical analysis of contemporary isotretinoin prescribing practices.

Daunton, A and Oyebode, F and Goulding, J M R (2019) Depression and the dermatologist: a critical analysis of contemporary isotretinoin prescribing practices. Clinical and experimental dermatology. ISSN 1365-2230. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Official URL: https://onlinelibrary.wiley.com/doi/abs/10.1111/ce...

Abstract

The management of patients with current or previous depression who require isotretinoin treatment for acne is a challenging area. Current opinion favours the view that isotretinoin-induced mood disturbance is a rare, idiosyncratic reaction, not reliably related to the presence of pre-existing depression. Nonetheless, in the absence of a definitive high-quality study, there remains a degree of legitimate uncertainty. With input from a psychiatrist, we created and administered a detailed survey featuring a range of low, medium and higher-risk clinical scenarios, designed to capture a snapshot of current dermatological practice. Respondents indicated a wide variability in their approach, with a substantial proportion referring on to psychiatry where this was not deemed necessary. Few dermatologists appreciated the importance of behaviours suggesting impaired impulse control. We hope this study helps to refine guidance for isotretinoin prescribing, both to maximise safety, and to ensure deserving patients with acne do not miss out on appropriate treatment. This article is protected by copyright. All rights reserved.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WR Skin. Dermatology
Divisions: Ambulatory Care > Dermatology
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Depositing User: Mr Philip O'Reilly
Date Deposited: 29 Mar 2019 13:06
Last Modified: 29 Mar 2019 13:06
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1974

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