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Pharmacotherapy for obesity in menopausal women.

Samat, Ashish and Rahim, Asad and Barnett, Anthony H (2008) Pharmacotherapy for obesity in menopausal women. Menopause international, 14 (2). pp. 57-62. ISSN 1754-0453. This article is accessible to all HEFT staff and students via NHS Evidence www.evidence.nhs.uk by using their HEFT Athens login IDs

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Official URL: http://min.sagepub.com/content/14/2/57.long

Abstract

Weight gain, during and after the menopause is common. Contributing factors include ethnicity, reduced physical activity, reduced lean mass, reduced resting metabolic rate and treatment with certain drugs, e.g. steroids, insulin, glitazones. Excess body weight increases the risk of medical conditions including type 2 diabetes, hypertension, osteoarthritis, certain cancers and is associated with increased mortality. This review examines pharmacological approaches to promote weight loss. Pharmacological therapy should be considered as an adjunct to diet and lifestyle changes. The licensed drugs orlistat, sibutramine and rimonabant are discussed. Obesity increases the risk of type 2 diabetes. Thus, the effects of metformin and exenatide are examined.

Item Type: Article
Additional Information: This article is accessible to all HEFT staff and students via NHS Evidence www.evidence.nhs.uk by using their HEFT Athens login IDs
Subjects: WK Endocrine system. Endocrinology
WP Gynaecology. Women’s health
Divisions: Ambulatory Care > Diabetes
Womens and Childrens
Related URLs:
Depositing User: Sophie Rollason
Date Deposited: 06 Jun 2014 11:09
Last Modified: 06 Jun 2014 11:09
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/192

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