Healthcare resource utilization by patients with treatment-refractory myasthenia gravis in England.

Harris, Linda and Graham, Sophie and MacLachlan, Sharon and Exuzides, Alex and Jacob, Saiju (2019) Healthcare resource utilization by patients with treatment-refractory myasthenia gravis in England. Journal of medical economics. p. 1. ISSN 1941-837X. This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs

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Official URL: https://www.tandfonline.com/doi/full/10.1080/13696...

Abstract

AIMS

To examine healthcare resource utilization associated with refractory myasthenia gravis (MG) in England.

MATERIALS AND METHODS

This was a retrospective cohort study of linked data from the Clinical Practice Research Datalink and the Hospital Episode Statistics database collected between 1997 and 2016. Included patients were ≥18 years of age at the index MG diagnosis. Patients with refractory MG were identified using an algorithm based on treatments received. Healthcare resource utilization since the index date was compared between refractory and non-refractory cohorts.

RESULTS

The study included 1,149 patients with MG, of whom 66 (5.7%) were refractory. Sex and age at diagnosis did not significantly differ between the refractory and non-refractory cohorts. Rates of healthcare resource utilization per person-year were significantly higher (p < 0.05) for patients with refractory than non-refractory MG for GP visits, visits to other healthcare professionals, outpatient visits, and inpatient hospitalization. Patients in the refractory cohort spent more total days hospitalized since the index visit than patients in the non-refractory cohort (median, 33 vs. 16 days [p < 0.0001]).

LIMITATIONS

The algorithm for identifying refractory patients did not include clinical criteria. Also, treatments administered in hospitals or by specialists were not available in the databases.

CONCLUSIONS

Patients in England with refractory MG more often visit healthcare providers, are hospitalized, and visit an emergency room than patients with non-refractory MG.

Item Type: Article
Additional Information: This article is available to all UHB staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their UHB Athens login IDs
Subjects: WL Nervous system. Neurology
Divisions: Emergency Services > Neurology
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Depositing User: Mr Philip O'Reilly
Date Deposited: 12 Mar 2019 15:27
Last Modified: 12 Mar 2019 15:27
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1915

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