Effectiveness and cost effectiveness of pharmacist input at the ward level: a systematic review and meta-analysis.

Dawoud, Dalia M and Smyth, Maria and Ashe, Joanna and Strong, Thomas and Wonderling, David and Hill, Jennifer and Varia, Mihir and Dyer, Philip and Bion, Julian (2018) Effectiveness and cost effectiveness of pharmacist input at the ward level: a systematic review and meta-analysis. Research in social & administrative pharmacy : RSAP. ISSN 1934-8150.

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Abstract

BACKGROUND

Pharmacists play important role in ensuring timely care delivery at the ward level. The optimal level of pharmacist input, however, is not clearly defined.

OBJECTIVE

To systematically review the evidence that assessed the outcomes of ward pharmacist input for people admitted with acute or emergent illness.

METHODS

The protocol and search strategies were developed with input from clinicians. Medline, EMBASE, Centre for Reviews and Dissemination, The Cochrane Library, NHS Economic Evaluations, Health Technology Assessment and Health Economic Evaluations databases were searched. Inclusion criteria specified the population as adults and young people (age >16 years) who are admitted to hospital with suspected or confirmed acute or emergent illness. Only randomised controlled trials (RCTs) published in English were eligible for inclusion in the effectiveness review. Economic studies were limited to full economic evaluations and comparative cost analysis. Included studies were quality-assessed. Data were extracted, summarised. and meta-analysed, where appropriate.

RESULTS

Eighteen RCTs and 7 economic studies were included. The RCTs were from USA (n = 3), Sweden (n = 2), Belgium (n = 2), China (n = 2), Australia (n = 2), Denmark (n = 2), Northern Ireland, Norway, Canada, UK and Netherlands. The economic studies were from UK (n = 2), Sweden (n = 2), Belgium and Netherlands. The results showed that regular pharmacist input was most cost effective. It reduced length-of-stay (mean = -1.74 days [95% CI: 2.76, -0.72], and increased patient and/or carer satisfaction (Relative Risk (RR) = 1.49 [1.09, 2.03] at discharge). At £20,000 per quality-adjusted life-year (QALY)-gained cost-effectiveness threshold, it was either cost-saving or cost-effective (Incremental Cost Effectiveness Ratio (ICER) = £632/QALY-gained). No evidence was found for 7-day pharmacist presence.

CONCLUSIONS

Pharmacist inclusion in the ward multidisciplinary team improves patient safety and satisfaction and is cost-effective when regularly provided throughout the ward stay. Research is needed to determine whether the provision of 7-day service is cost-effective.

Item Type: Article
Subjects: QV Pharmacology
WD Diseases and disorders of systemic, metabolic or environmental origin > WD400 Emergency medicine
Divisions: Ambulatory Care > Diabetes
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Depositing User: Mrs Yolande Brookes
Date Deposited: 09 Nov 2018 15:22
Last Modified: 09 Nov 2018 15:22
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1778

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