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Reactivity of Routine HIV Antibody Tests in Children with Perinatally-Acquired HIV-1 in England: Cross Sectional Analysis.

Fidler, Katy and Foster, Caroline and Lim, Emma J and Patel, Amie and Welch, Steven B and Menson, Esse and Klein, Nigel and Judd, Ali (2018) Reactivity of Routine HIV Antibody Tests in Children with Perinatally-Acquired HIV-1 in England: Cross Sectional Analysis. The Pediatric infectious disease journal. ISSN 1532-0987. This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs

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Official URL: https://journals.lww.com/pidj/Abstract/publishahea...

Abstract

We assessed HIV antibody prevalence in children with perinatally-acquired HIV (PaHIV) in England. 18%(10/55) of those starting combination antiretroviral therapy (cART) <6 months of age were seronegative, and had lower viral load at diagnosis and cART start, and fewer viral rebounds, than 45/55 seropositives. Implications for patient selection for HIV cure research, and interpretation of routine antibody testing, are discussed.

Item Type: Article
Additional Information: This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs
Subjects: WD Diseases and disorders of systemic, metabolic or environmental origin > WD350 Immunologic diseases
Divisions: Clinical Support > Infectious Diseases
Related URLs:
Depositing User: Miss Emily Johnson
Date Deposited: 14 Sep 2018 12:53
Last Modified: 14 Sep 2018 12:53
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1739

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