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Risk of Recurrent Disease and Surgery Following an Admission for Acute Diverticulitis.

El-Sayed, Charlotte and Radley, Simon and Mytton, Jemma and Evison, Felicity and Ward, Stephen T (2018) Risk of Recurrent Disease and Surgery Following an Admission for Acute Diverticulitis. Diseases of the colon and rectum, 61 (3). pp. 382-389. ISSN 1530-0358. Available to HEFT Athens users

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Abstract

BACKGROUND

Diverticular disease accounts for significant morbidity and mortality and may take the form of recurrent episodes of acute diverticulitis. The role of elective surgery is not clearly defined.

OBJECTIVE

This study aimed to define the rate of hospital admission for recurrent acute diverticulitis and risk factors associated with recurrence and surgery.

DESIGN

This is a retrospective population-based cohort study.

SETTINGS

National Health Service hospital admissions for acute diverticulitis in England between April 2006 and March 2011 were reviewed.

PATIENTS

Hospital Episode Statistics data identified adult patients with the first episode of acute diverticulitis (index admission), and then identified recurrent admissions and elective or emergency surgery for acute diverticulitis during a minimum follow-up period of 4 years. Exclusion criteria included previous diagnoses of acute diverticulitis, colorectal cancer, or GI bleeding, and prior colectomy or surgery or death during the index admission.

INTERVENTIONS

There were no interventions.

MAIN OUTCOME MEASURES

The primary outcomes measured were recurrent admissions for acute diverticulitis and patients requiring either elective or emergency surgery during the study period.

RESULTS

Some 65,162 patients were identified with the first episode of acute diverticulitis. The rate of hospital admission for recurrent acute diverticulitis was 11.2%. A logistic regression model examined factors associated with recurrent acute diverticulitis and surgery: patient age, female sex, smoking, obesity, comorbidity score >20, dyslipidemia, and complicated acute diverticulitis increased the risk of recurrent acute diverticulitis. There was an inverse relationship between patient age and recurrence. Similar factors were associated with elective and emergency surgery.

LIMITATIONS

The cases of acute diverticulitis required inpatient management and the use of Hospital Episode Statistics, relying on the accuracy of diagnostic coding.

CONCLUSIONS

This is the largest study assessing the rates of hospital admission for recurrent acute diverticulitis. Knowledge of the rate and risk factors for recurrent acute diverticulitis is required to aid discussion and decision making with patients regarding the need and timing of elective surgery. Some factors associated with recurrence are modifiable; therefore, weight reduction and smoking cessation can be championed. See Video Abstract at http://links.lww.com/DCR/A449.

Item Type: Article
Additional Information: Available to HEFT Athens users
Subjects: WI Digestive system. Gastroenterology
Divisions: Planned IP Care > Gastroentrology
Related URLs:
Depositing User: Miss Emily Johnson
Date Deposited: 11 May 2018 15:21
Last Modified: 11 May 2018 15:21
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1653

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