HEFT Repository

Unexplained abnormal liver function in patients with primary antibody deficiency: could it be chronic hepatitis E infection?

Mohamed, Omar E and Jones, Julie and Osman, Husam and Huissoon, Aarnoud P (2017) Unexplained abnormal liver function in patients with primary antibody deficiency: could it be chronic hepatitis E infection? Journal of clinical pathology. ISSN 1472-4146. This article is available to all HEFT staff and students via ASK HEFT Discovery tool http://tinyurl.com/z795c8c using their HEFT Athens Login.

Full text not available from this repository.
Official URL: http://jcp.bmj.com/content/early/2017/08/09/jclinp...

Abstract

Data from recent studies suggest rising incidence rate of hepatitis E virus (HEV) infection in the UK. HEV infection may take a severe and persistent course in immunocompromised patients, including transplant recipients on immunosuppressives, patients with HIV, haematological malignancies and in idiopathic CD4(+) T lymphocytopenia. The prevalence of HEV in primary antibody deficiency (PAD) disorders is still unknown. The aim of this study was to investigate HEV infection in 27 patients with PAD with unexplained, persistently elevated liver enzymes. Although all the 27 patients tested negative for HEV-RNA, we would still strongly recommend that HEV should be considered in any immunodeficient patient with impaired liver function.

Item Type: Article
Additional Information: This article is available to all HEFT staff and students via ASK HEFT Discovery tool http://tinyurl.com/z795c8c using their HEFT Athens Login.
Subjects: QW Microbiology. Immunology
Divisions: Emergency Services > Renal
Related URLs:
Depositing User: Mr Philip O'Reilly
Date Deposited: 24 Nov 2017 16:12
Last Modified: 24 Nov 2017 16:12
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1525

Actions (login required)

View Item View Item