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Type 2 diabetes in adolescents and young adults.

Lascar, Nadia and Brown, James and Pattison, Helen and Barnett, Anthony H and Bailey, Clifford J and Bellary, Srikanth (2017) Type 2 diabetes in adolescents and young adults. The lancet. Diabetes & endocrinology. ISSN 2213-8595. This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs

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Official URL: http://www.thelancet.com/journals/landia/article/P...

Abstract

The prevalence of type 2 diabetes in adolescents and young adults is dramatically increasing. Similar to older-onset type 2 diabetes, the major predisposing risk factors are obesity, family history, and sedentary lifestyle. Onset of diabetes at a younger age (defined here as up to age 40 years) is associated with longer disease exposure and increased risk for chronic complications. Young-onset type 2 diabetes also affects more individuals of working age, accentuating the adverse societal effects of the disease. Furthermore, evidence is accumulating that young-onset type 2 diabetes has a more aggressive disease phenotype, leading to premature development of complications, with adverse effects on quality of life and unfavourable effects on long-term outcomes, raising the possibility of a future public health catastrophe. In this Review, we describe the epidemiology and existing knowledge regarding pathophysiology, risk factors, complications, and management of type 2 diabetes in adolescents and young adults.

Item Type: Article
Additional Information: This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs
Subjects: WK Endocrine system. Endocrinology
Divisions: Ambulatory Care > Diabetes
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Depositing User: Mrs Caroline Tranter
Date Deposited: 24 Nov 2017 11:29
Last Modified: 24 Nov 2017 11:29
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1508

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