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Retinal and vitreous metastases from hepatocholangiocarcinoma.

Praidou, Anna and Jacob, Sarita and Irion, Luciane and Sivaraj, Ramesh R and Groenewald, Carl and Coupland, Sarah E and Heimann, Heinrich (2017) Retinal and vitreous metastases from hepatocholangiocarcinoma. BMC cancer, 17 (1). p. 430. ISSN 1471-2407. This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs

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Official URL: https://bmccancer.biomedcentral.com/

Abstract

BACKGROUND

To report a case of metastatic hepatocholangiocarcinoma to the vitreous and retina.

CASE PRESENTATION

A 70-year-old male, who was recently diagnosed with hepatocholangiocarcinoma, was complaining of floaters in his right eye over the past 5 months and was referred to the Liverpool Ocular Oncology Centre. On presentation, his visual acuity in the right eye was 6/24. Fundus exam revealed a whitish, unilateral, full-thickness retinal lesion at the inferotemporal arcade of his right eye, with vitreous infiltration and subretinal fluid. The patient underwent 25G pars plana vitrectomy with biopsy, resection of the lesion and intravitreal bevacizumab injection. Histopathology testing of the surgical specimens confirmed the diagnosis of metastatic carcinoma to the eye. Two months postoperatively his visual acuity had improved to 6/7.5 and there was no sign of active disease in his right eye, while 9 months postoperatively his visual acuity decreased to 6/9.5 due to developing nuclear sclerotic cataract in his right eye.

CONCLUSION

The current report presents the first case of a hepatocholangiocarcinoma metastasis to the vitreous and retina.

Item Type: Article
Additional Information: This article is available to all HEFT staff and students via ASK Discovery tool http://tinyurl.com/z795c8c by using their HEFT Athens login IDs
Subjects: WW Eyes. Ophthalmology
Divisions: Ambulatory Care > Ophthalmology
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Depositing User: Mrs Caroline Tranter
Date Deposited: 23 Jun 2017 15:32
Last Modified: 23 Jun 2017 15:32
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1426

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