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A case-control study of medical, psychological and socio-economic factors influencing the severity of chronic rhinosinusitis.

Philpott, Carl and Erskine, Sally and Hopkins, Claire and Coombes, Emma and Kara, Naveed and Sunkareneni, Vishnu and Anari, Shahram and Salam, Mahmoud and Farboud, Amir and Clark, Allan (2016) A case-control study of medical, psychological and socio-economic factors influencing the severity of chronic rhinosinusitis. Rhinology, 54 (2). pp. 134-40. ISSN 0300-0729. This article is available to all HEFT staff and students via ASK HEFT Discovery tool http://tinyurl.com/z795c8c using their HEFT Athens Login.

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Official URL: http://www.rhinologyjournal.com/Abstract.php?id=14...

Abstract

BACKGROUND

Chronic rhinosinusitis (CRS) is a common and debilitating disorder. Little is known about the epidemiology of this disease. The aims of the study were to identify differences in socio-economic variables and quality of life between patients with chronic rhinosinusitis and healthy controls, to identify any significant associations between CRS and other medical co-morbidities, psychiatric disease or environmental exposure and to explore the experience of CRS from the perspective of CRS sufferers.

METHODS

Participants were recruited from ENT clinics from 30 centres across the UK. They completed a study-specific questionnaire considering environmental, medical and socio-economic factors, and SF-36 and SNOT-22 scores. All participants with CRS were diagnosed by a clinician and categorised as having CRS (with polyposis, without polyposis or allergic fungal rhinosinusitis (AFRS)). Controls included family and friends of those attending ENT outpatient clinics and hospital staff who had no diagnosis of nose or sinus problems and had not been admitted to hospital in the previous 12 months.

RESULTS

A total of 1470 study participants (1249 patients and 221 controls) were included in the final analysis. Highly significant differences were seen in generic and disease-specific quality of life scores between CRS sufferers and controls; mean SNOT-22 score 45.0 for CRS compared with 12.1 amongst controls. There were no clear differences in socioeconomic variables including social class, index of multiple deprivation and educational attainment between cases and controls. Common comorbidities with a clear association included respiratory and psychiatric disorders, with a higher frequency of reported upper respiratory tract infections.

CONCLUSIONS

CRS is associated with significant impairment in quality of life and with certain medical co-morbidities. In contrast to other common ENT disorders, no socioeconomic differences were found between patients and controls in this study.

Item Type: Article
Additional Information: This article is available to all HEFT staff and students via ASK HEFT Discovery tool http://tinyurl.com/z795c8c using their HEFT Athens Login.
Subjects: WV Otorhinolaryngology. ENT medicine
Divisions: Ambulatory Care > ENT
Related URLs:
Depositing User: Miss Adele Creak
Date Deposited: 03 Mar 2017 14:01
Last Modified: 03 Mar 2017 14:01
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1235

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