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A multicentre study of the precision and accuracy of the TruSlice and TruSlice Digital histological dissection devices.

Orchard, G E and Shams, M and Nwokie, T and Fernando, P and Bulut, C and Quaye, C J and Gabriel, J and Ramji, Z and Georgaki, A and Watt, M and Cole, Z and Stewart, K and McTaggart, V and Padayachy, S and Long, A M and Ogden, A and Andrews, Claire and Birchall, A and Shams, F and Neesam, H and Haine, N (2016) A multicentre study of the precision and accuracy of the TruSlice and TruSlice Digital histological dissection devices. British journal of biomedical science, 73 (4). pp. 163-167. ISSN 0967-4845. This article is available to all HEFT staff and students via ASK HEFT Discovery tool http://tinyurl.com/z795c8c using their HEFT Athens Login.

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Official URL: http://www.tandfonline.com/doi/abs/10.1080/0967484...

Abstract

BACKGROUND

Five key factors enabling a good surgical grossing technique include a flat uniformly perpendicular specimen cutting face, appropriate immobilisation of the tissue specimen during grossing, good visualisation of the cutting tissue face, sharp cutting knives and the grossing knife action. TruSlice and TruSlice Digital are new innovative tools based on a guillotine configuration. The TruSlice has plastic inserts whilst the TruSlice Digital has an electronic micrometre attached: both features enable these dissection factors to be controlled. The devices were assessed in five hospitals in the UK.

MATERIAL AND METHODS

A total of 267 fixed tissue samples from 23 tissue types were analysed, principally the breast (n = 32) skin (30), rectum (28), colon (27) and cervix (17). Precision and accuracy were evaluated by measuring the defined thickness, and the consistency of achieving the defined thickness of tissue samples taken respectively. Both parameters were expressed as a total percentage of compliance for the cohort of samples accessed.

RESULTS

Overall, the mean (standard deviation) score for precision was 81 (11) % whilst the accuracy score was 82 (11) % (both p < 0.05, chi-squared test), although this varied with type of tissue. Accuracy and precision were strongly correlated (rp = 0.83, p < 0.001).

CONCLUSION

The TruSlice Digital devices offer an assured precision and accuracy performance which is reproducible across an assortment of tissue types. The use of a micrometre to set tissue slice thickness is innovative and should comply with laboratory accreditation requirements, alleviating concerns of how to tackle issues such as the 'measurement of uncertainty' at the grossing bench.

Item Type: Article
Additional Information: This article is available to all HEFT staff and students via ASK HEFT Discovery tool http://tinyurl.com/z795c8c using their HEFT Athens Login.
Subjects: QZ Pathology. Oncology
Divisions: Clinical Support > Pathology
Related URLs:
Depositing User: Miss Adele Creak
Date Deposited: 03 Mar 2017 11:02
Last Modified: 03 Mar 2017 11:02
URI: http://www.repository.heartofengland.nhs.uk/id/eprint/1219

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